Toad Poisoning in Dogs – Dogs are comparatively more likely to get Toad Poisoning. Dogs often catch toads in their mouths because they are natural predators, showing themselves to the toxin that the toad releases when it feels threatened. Most frequently absorbed via the membrane of the oral cavity, this highly toxic defense chemical can also enter the eyes and damage vision. If left untreated, its effects can be fatal. The Colorado River Toad (Bufo alvarius) and the Marine Toad (Bufo marinus) are the two most dangerous toad species that are well-known to have harmful effects on pets. The warmest months, when toad activity is higher and humidity is higher, are when most of the toad poisoning cases are reported.